Viral Polymerases

- Structures, Functions and Roles as Antiviral Drug Targets

Forfatter: info mangler
Bog
  • Format
  • Bog, paperback
  • Engelsk

Beskrivelse

Viral Polymerases: Structures, Functions and Roles as Antiviral Drug Targets presents in-depth study information on the structure and functions of polymerases and their roles in the lifecycle of viruses, and as drug targets. Viral polymerases constitute a vital component in the lifecycle of many viruses, such as human immunodeficiency virus (HIV), hepatitis viruses, influenza virus, and several others. They are essentially required for the replication of viruses. Thus, the polymerases that can be found in viruses (called viral polymerases) represent favorable targets for the design and development of antiviral drugs.

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Detaljer
  • SprogEngelsk
  • Sidetal496
  • Udgivelsesdato01-11-2018
  • ISBN139780128154229
  • Forlag Academic Press Inc
  • FormatPaperback
Størrelse og vægt
  • Vægt770 g
  • coffee cup img
    10 cm
    book img
    15,1 cm
    22,9 cm

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    Polio Drug design Molecular dynamics. Coronavirus Herpes simplex virus Adenoviruses Vaccinia virus Encephalitis Reverse transcriptase Inhibitors Drug Resistance Drug Discovery RNA polymerases Picornaviridae Flavivirus Ebola virus Zika Virus Hepatocellular carcinoma (HCC) Structure-based drug design Chikungunya RNA-POLYMERASE Antivirals DNA-POLYMERASE Antiviral strategies Crystal structure RNAse RNA replication Exonuclease Protein structure/function Human Immunodeficiency Virus Inhibitor Homology Modeling RNA dependent RNA polymerase Hepatitis c virus (HCV) 3DPol crystal structure 3Dpol inhibitors Adenovirus antivirals Adenovirus replication Adenovirus diagnosis allosteric inhibitors Antipolio drugs Alphaviruses Anti-HBV drugs Atomistic-level modeling Alphaviral diseases DENV RdRP Direct-acting antivirals (DAAs) Falviviridae Herpes simplex virus (HSV) HBV life cycle HBV genome HBV Polymerase HBV mutants HBV polymerase inhibitors L-protein Nonsegmented genomes Nucleoside inhibitors Nucleoside/nucleotide inhibitors (NIs) HSV polymerase Polymerase inhibitors Nonstructural proteins Poxvirus polymerase Interferon (IFN) HBV Replication Severe Acute Respiratory Syndrome Coronavirus RNA-dependent RNA polymerase (3Dpol) Herpesvirus polymerase Ribavirin (RBV) Viral Hemorrhagic Fever Viral polymerase Negative-strand RNA polymerase Nonnucleoside/nonnucleotide inhibitors (NNIs) Middle East Respiratory Syndrome Coronavirus Nonnucleoside inhibitors RNA-dependent RNA polymerases (RdRPs) Nonstructural (NS) protein Segmented genomes nucleoside analogs Rhinovirus ZIKV polymerase

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