Total Synthesis of Bioactive Natural Products

Designed as a basic reference for natural product and medicinal chemists, this timely handbook is the first to systematically distill the key information from the thousands of primary research articles published on natural products each year.

The author has assembled the core chemical and pharmaceutical characteristics of 100 of the most pharmaceutically relevant natural products.

For each compound, specially drawn full synthesis schemes, including alternative synthesis routes if applicable, capture the key chemical knowledge, so that students can quickly find the necessary information, while advanced researchers can compare and assess the potential of different compounds for any given task. The lead compounds, drug candidates, and marketed drugs developed from the compounds are also described, as are pharmaceutical effects of the primary compound. All compound entries follow a coherent and highly consistent layout and contain selected references to the primary chemical and pharmaceutical literature, making the handbook easy and intuitive to use.