Single-Arm Phase II Survival Trial Design

  • Format
  • E-bog, ePub
  • Engelsk
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Beskrivelse

Single-Arm Phase II Survival Trial Design provides a comprehensive summary to the most commonly- used methods for single-arm phase II trial design with time-to-event endpoints. Single-arm phase II trials are a key component for successfully developing advanced cancer drugs and treatments, particular for target therapy and immunotherapy in which time-to-event endpoints are often the primary endpoints. Most test statistics for single-arm phase II trial design with time-to-event endpoints are not available in commercial software. Key Features: Covers the most frequently used methods for single-arm phase II trial design with time-to-event endpoints in a comprehensive fashion. Provides new material on phase II immunotherapy trial design and phase II trial design with TTP ratio endpoint. Illustrates trial designs by real clinical trial examples Includes R code for all methods proposed in the book, enabling straightforward sample size calculation.

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Detaljer
  • SprogEngelsk
  • Sidetal273
  • Udgivelsesdato19-07-2021
  • ISBN139781000422481
  • Forlag Crc Press
  • FormatePub

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