Studiebog
    Pseudokinases

    Pseudokinases

    - Volume 667

    Forfatter: info mangler
    Bog
    • Format
    • Bog, hardback
    • Engelsk

    Beskrivelse

    Pseudokinases, Volume 667, the latest release in the Methods in Enzymology serial, highlights new advances in the field with this new volume presenting interesting chapters, including the Production and Purification of the PEAK pseudokinases for structural and functional studies, Structural biology and biophysical characterization of Tribbles pseudokinases, Detecting endogenous TRIB protein expression and its downstream signaling, Analysis of human Tribbles 2 pseudokinase, Expression, purification and examination of ligand-binding to IRAK pseudokinases, Characterization of pseudokinase ILK-mediated actin assembly, Biochemical examination of Titin pseudokinase, Approaches to study pseudokinase conformations, CRISPR editing cell lines for reconstitution studies of pseudokinase function, and much more.

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    Detaljer
    • SprogEngelsk
    • Sidetal836
    • Udgivelsesdato09-05-2022
    • ISBN139780323915410
    • Forlag Academic Press Inc
    • FormatHardback
    Størrelse og vægt
  • Vægt1450 g
    • coffee cup img
    10 cm
    book img
    15,2 cm
    22,9 cm

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    Screening Cancer Crystallization. Crystallography Cell death X-ray crystallography Computational biology Regulation Membrane proteins Conformation Cell adhesion Phosphorylation Bioinformatics Flow cytometry Acute myeloid leukemia Mitosis Protein Structure Signaling Drug Discovery AKT Dimerization Gene Editing Protein purification Protein crystallization Cas9 CRISPR/CAS9 Webserver Allosteric MEK Baculovirus Function Genome editing Complémentation Innate immunity Assay Kinase Scaffolds High-throughput screening ITC CRISPR-Cas9 Thermal stability RAF Growth factor Necroptosis Allostery Integrin EGFR Protein expression Ligand binding Evolutionary constraints Mouse models Cryo-electron microscopy CGMP Oligomerization Target engagement Western blotting Cell signaling HER2 Fluorescence polarization Inhibitor Receptor tyrosine kinases Kinase Inhibitors Inhibitor-Screening CRISPR Structural biology Isothermal titration calorimetry Kinetochores TSA DSF Actin bundling Activity-based probes Bacterial protein expression ATP displacement Biolayer-interferometry (BLI) Allelic series BUBR1 Atypical kinases Ba/F3 cells Coupled-enzyme assay Bud32 CETSA Caulobacter crescentus Deucravacitinib FSBA-cell lysate inactivation Galloway-Mowat syndrome HTRF probe Differential scanning fluorimetry HER3 KeywordPseudokinases Kinase homology domain KSR In silico protein stability calculation Interleukin-1 receptor (IL1R) IRAK2 IRAK3 Janus kinase family Kinase activation leucine zipper Luminescence-based phosphotransfer activity assays Histidine kinase Human epidermal growth factor receptors HER receptors Orthosteric site Hydrogen-deuterium exchange PEAK pseudokinases Pseudokinase Pseudoenzymes ILK recombinant Interfacial sites PP2A Receptor guanylyl cyclase Structural mass spectrometry SCYL2 SCYL3 Sf21 cells Toll-Like Receptor (TLR) TYK2-JH2 Swarm plate assay t6A Tribbles TYK2-JH2 PSEUDOKINASE DOMAIN BINDERS TRIB1 Zombie proteins Uncharacterized proteins KEOPS Thermal shift assay Medium-throughput cloning MLKL Molecular glues Protein–drug interaction Small Molecule Drugs two-component system Pseudokinases Receptor tyrosine kinase (RTK) SBDD SCYL1 TYK2 TRIB2 tRNA modification

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