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Beskrivelse
Long Noncoding RNAs: Basic Science to Disease Biology provides an overview of the state-of-the-art methods in the field that have created an understanding of the sequence, structure, function and disease associations of lncRNAs. The decade following the availability of the reference human genome has seen tremendous advancements in the scale and throughput of nucleotide sequencing and its widespread application. This sequencing technology has allowed for rapid, advanced study of the functionalities of lncRNAs and has revealed their intricate and important roles in a variety of biological processes and pathophysiology of diseases.
Features approaches to characterize the function of lncRNAPresents information on high-throughput functional screening and imagingIncludes a chapter on RNA-Capture Seq for the annotation of lncRNAs