Genomics and Clinical Diagnostics

With large genome initiatives being announced around the world, this book provides a timely graduate level introduction to molecular diagnostics technologies and applications to enable readers to embrace the subject and original literature. The first of four sections delivers readily accessible introductory information on the purposes, properties and drawbacks of diagnostic tests followed by chapters on the principal molecular technologies that underpin the information in the later sections. The following two sections provide more specialised examples of currently used diagnostic technologies and insights into selected key diagnostic challenges including specific examples, automation and point of care testing. The book concludes with a section on future prospects focusing on mutation detection for personalised medicine, for example in cancer.