er zhong lei xing shen jing jing shen yi chuan bing yi gan wei dian de yan jiu

dan chun xing dian xian da fa zuo PGME pure grand mal epilepsy shi dian xian te yi xing da fa zuo de chang jian ya xing zhi yi ju you fu za de yi chuan fang shi ben zhu zuo bao dao le dui yi ge dan chun xing dian xian da fa zuo de da jia xi jin xing de quan ji yin zu chang ran se ti de sao miao yan jiu zai xian xing yi chuan mo shi he 65 de wai xian lv de tiao jian xia yu 11q22 1 23 3 qu yu guan cha dao lian xu xing de 7 ge yi chuan duo tai xing biao ji LOD zhi 1 0 0 liang dian fa zai D11S4159 chu de dao zui da de LOD zhi wei 1 99 0 duo dian fa fen xi zui da de LOD zhi wei 2 18 0 luo zai D11S1782 he D11S3178 zhi jian jie guo ti shi 11q22 1 23 3 ke neng shi yi ge xin de dan chun xing dian xian da fa zuo yi gan wei dian jing shen fen lie zheng SCZ schizophrenia shi yi zhong chang jian de jing shen xing ji bing dan qi jin wei zhi reng ran mei you zhao dao ren he zhi bing ji yin T fu he wu dan bai 1 TCP1 T complex protein 1 ji yin shi yi ge gao du bao shou de ji yin qi bian ma dan bai zai xi bao gu jia de wei chi he shen jing di zhi de chuan di zhong ju you zhong yao de zuo yong jin lai de yan jiu fa xian T fu he wu dan bai 1 zai jing shen fen lie zheng huan zhe hai ma zu zhi zhong biao da zeng jia ben zhu zuo dui gai ji yin de liang ge chang jian de SNPs wei dian rs4832 and rs15982 yu jing shen fen lie zheng de xiang guan xing jin xing le tan tao tong guo dui 380 li bing ren he 322 wei jian kang dui zhao zhe jin xing dui bi yan jiu fa xian rs15982 wei dian de deng wei ji yin pin lv you rs4832 he rs15982 gou jian de dan bei ti xing pin lv zai huan zhe he dui zhao zu zhi jian you xian zhu xing de cha yi p 0 00023 p 0 000002 bing qie rs15982 de CT CC ji yin xing pin lv tong yang cun zai xian zhu xing de cha yi p 0 011 p 0 00017