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PART I: Introduction, selection, mechanisms.
1. Cell-penetrating peptides
Matjaz Zorko and ?lo Langel
2. Shuttling homeoproteins and their biological significance
Alain Prochiantz and Ariel Di Nardo
3. Artificial evolutionary optimization process to improve the functionality of CPPs
Niels R?ckendorf, Katrin Ramaker, and Andreas Frey
4. In silico design of chemically modified cell penetrating peptides
Vinod Kumar, Gajendra Pal Singh Raghava
5. Synthetic Molecular Evolution of Cell Penetrating Peptides
William C. Wimley
6. A native CPP from rattlesnake with therapeutic and theranostic properties
Lucas C. Porta, Joana D'Arc Campeiro, and Mirian A. F. Hayashi
7. Synthesis of cell-penetrating peptide coated silica nanoparticles and their physicochemical and biological characterization
Isabel Gessner, Annika Klimpel and Ines Neundorf
8. Enhancing the therapeutic potential of extracellular vesicles using peptide technology
Carla Martin-Perez, Mariana Concei??o, Richard Raz, Matthew J. A. Wood, and Thomas C. Roberts
9. Challenges and methods for the study of CPP translocation mechanisms
Astrid Walrant, Fran?oise Illien, Sandrine Sagan, and Nicolas Rodriguez
10. Membrane molecular interactions and induced structures of CPPs
Fatemeh Madani and Astrid Gr?slund
11. A single GUV method for revealing the action of cell-penetrating peptides in biomembranes
Md. Mizanur Rahman Moghal, Madhabi Lata Shuma, Md. Zahidul Islam, and Masahito Yamazaki
12. Methods for Small-Angle Scattering Measurements on Peptiplexes of DNA with Cell-Penetrating Peptides
Emerson R.Silva, Lucas R. Mello, and Ian Hamley
13. Imaging CPP delivery mechanisms of oligonucleotides
Najoua El Boujnouni, Alexander H. van Asbeck, J?rgen Dieker, Derick G. Wansink, and Roland Brock
14. Quantitative subcellular analysis of cyclic cell-penetrating peptide EJP18 in non-adherent cells
Edward J. Sayers, Victoria L. Barlow, Yu-Hsuan Tsai, and Arwyn T. Jones
15. PepFect14: signaling and transfection
Luca Falato, Maxime Gestin, and ?lo Langel
16. Utilisation of cell-penetrating peptides for in vivo delivery of bioactive cargo - the effect of nanoparticle formulation
Piret Arukuusk, Heleri Heike H?rk, and ?lo Langel
Part II: Delivery of proteins and protein mimics.
17. Protein delivery by PTDs/CPPs
Caroline Palm-Apergi and Steve F. Dowdy
18. Protein Delivery to Cytosol by Cell-Penetrating Peptide Bearing a Tandem Repeat Penetration-Accelerating Sequence
Akiko Okuda and Shiroh Futaki
19.Recombinant transcription factors (TFs) fused to ZEBRA minimal transduction domain (MD) for modulation of mRNA transcripts.
Benjamin Caulier, Jean-Luc Lenormand, and David Laurin
20. Protein mimicry and the design of bioactive cell penetrating peptides: The genesis of STOPSPERM bioportides
John Howl*, Joana Vieira Silva, , Margarida Fardilha, and Sarah Jones
21. Lipopeptide pepducins as therapeutic agents
Emily Michael, Lidija Covic, and Athan Kuliopulos
22. Delivery of Antibiotics by Cell-Penetrating Peptides to Kill Intracellular Pathogens
Christian R?ter
23. CPP applications in immune modulation and disease therapy
Ja-Hyun Koo, Won-Ju Kim, and Je-Min Choi
Part III: Targeting