Breakthrough

It is 1919, and Elizabeth Hughes, the 11-year-old daughter of America's most distinguished jurist and politician, Charles Evans Hughes, has been diagnosed with juvenile diabetes. It is essentially a death sentence. The only accepted form of treatmentstarvationwhittles her down to 45 pounds of skin and bones. Miles away, Canadian researchers Frederick Banting and Charles Best manage to identify and purify insulin from animal pancreasesa miracle soon marred by scientific jealousy, intense business competition, and fist fights. In a race against time and a ravaging disease, Elizabeth becomes one of the first diabetics to receive insulin injectionsall while its discoverers and a little-known pharmaceutical company struggle to make it available to the rest of the world. Relive the heartwarming true story of the discovery of insulin as it has never before been told, written with authentic detail and suspense, and featuring walk-ons by William Howard Taft, Woodrow Wilson, and Eli Lilly, among many others.