Biometals in Neurodegenerative Diseases

- Mechanisms and Therapeutics

Forfatter: info mangler
Bog
  • Format
  • Bog, hardback
  • Engelsk

Beskrivelse

Biometals in Neurodegenerative Diseases: Mechanisms and Therapeutics is an authoritative and timely resource bringing together the major findings in the field for ease of access to those working in the field or with an interest in metals and their role in brain function, disease, and as therapeutic targets. Chapters cover metals in Alzheimer’s Disease, Parkinson’s Disease, Motor Neuron Disease, Autism and lysosomal storage disorders. This book is written for academic researchers, clinicians and advanced graduate students studying or treating patients in neurodegeneration, neurochemistry, neurology and neurotoxicology. The scientific literature in this field is advancing rapidly, with approximately 300 publications per year adding to our knowledge of how biometals contribute to neurodegenerative diseases. Despite this rapid increase in our understanding of biometals in brain disease, the fields of biomedicine and neuroscience have often overlooked this information. The need to bring the research on biometals in neurodegeneration to the forefront of biomedical research is essential in order to understand neurodegenerative disease processes and develop effective therapeutics.

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Detaljer
  • SprogEngelsk
  • Sidetal462
  • Udgivelsesdato28-04-2017
  • ISBN139780128045626
  • Forlag Academic Press Inc
  • FormatHardback
Størrelse og vægt
  • Vægt1130 g
  • coffee cup img
    10 cm
    book img
    19,1 cm
    23,5 cm

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    Metal Magnesium Drug Brain Aging Dementia Inflammation Iron Metals Ros Alzheimer Cerebrospinal Fluid Neurodegenerative Diseases Spinal cord Parkinson's disease Chronic wasting disease Heavy metals Copper Magnetic resonance imaging Manganese Antioxidants Macrophages Amyloid Arsenic Mitochondria Exposure Bioinorganic chemistry Amyotrophic lateral sclerosis Ions Central Nervous System Selenium Creutzfeldt-Jakob disease Lead Autophagy Gaucher Disease Huntington's Disease Aggregation Metallothionein Autism spectrum disorders Gadolinium Neuronal ceroid-lipofuscinosis Alzheimers asd PH Parkinsons Alzheimer's disease Reactive Oxygen Species Occupational & Prion protein Protein degradation Selenoproteins Metal transporters Biokinetics Neurotoxicity Psychiatric Disorders Alpha-synuclein Biometals Contrast Agents Coordination Chemistry Lysosome Enzyme Selenocysteine Neurodegeneration Amyloid precursor protein Amyloid-Beta Multifunctional Htt MSN Encephalopathies ApoE and cancer aluminium toxicity Barker's hypothesis arginase ATP7B bovine spongiform Amyloid-β Batten Disease ceruloplasmin developmental origin Clioquinol clinically isolated syndrome (CIS) HFE homeostatic control Iron Transporters maganese metal chelator neurodegeneration with brain iron accumulation neurodegenerative dieases nonceruloplasmin copper progressive multiple sclerosis Huntingtin redox reaction Metabolic functions oxidative stress (OS) relapsing-remitting multiple sclerosis (RRMS) metal-based therapies silent neurotoxicity SHANK3

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