Læs og lyt til tusindvis af e- og lydbøger med Saxo Premium Stream e- og lydbøger Prøv gratis

Total Synthesis of Plakortide E and Biomimetic Synthesis of Plakortone B

af

Du sparer 35% Du sparer 35%
Total Synthesis of Plakortide E and Biomimetic Synthesis of Plakortone B
  • kr. 1.299,95
  • Leveringstid 5-7 hverdage
  • Forventet levering 28-09-2018
  • 35%
  • Bog, hardback (kr. 849,95) (kr. 849,95)
    1. Beskrivelse

      In his thesis, Xiaoyu Sun conducts the first total synthesis of all possible stereoisomers of plakortide E and also confirms the absolute configuration of natural plakortide E. Xiaoyu Sun subsequently converts Plakortide E methyl ester to plakortone B in a biomimetic conversion. Construction and functionalization of cyclic peroxides are notoriously difficult due to the very low O-O bond dissociation energy. Plaktoride E is isolated from the Jamaican marine sponge platorits halichondrioides and contains a five-membered peroxide ring, with oxygen atoms linked to tertiary C4 and C6 centers. The methodology used for synthesizing highly substituted cyclic peroxides is novel and useful, and not only extends the field of Pd-catalyzed reactions, but also provides a convenient synthetic approach for the preparation of the 1,2-dioxolanes series. Plakortide E and plakortone B are bioactive, which means that the synthetic studies on them and their analogs are pivotal in drug discovery.

      Andre udgaver:

      Bog, hæftet
      E-bog, PDF

    2. Yderligere info
      Udgivelsesdato:
      01-01-2012
      Sprog:
      Engelsk
      ISBN13:
      9783642271946
      Sidetal:
      236
      Vægt:
      508 g
      Dybde:
      14 mm
      Bredde:
      156 mm
      Højde:
      234 mm
      Forlag:
      Springer
      Mærkat:
      Bog, hardback
      Format:
      Hardback
    3. Anmeldelser

    Fandt du ikke hvad du søgte?

    Hvis denne bog ikke er noget for dig, kan du benytte kategorierne nedenfor til at finde andre titler. Klik på en kategori for at se lignende bøger.