Excerpt from The Journal of Laryngology, Rhinology and Otology, 1910, Vol. 25: An Analytical Record of Current Literature Relating to the Throat, Nose, and Ear
Meanwhile, however, former cultures were being tested for virulence by Professor Hewlett, and one culture (made Apri... l 4) was reported to be practically non-virulent, and a second culture which gave ordinary bare and beaded diphtheritic organisms was purified by subculturing, and Prof. Hewlett reported that the result of inoculation is that '5 of a forty eight-hour broth culture killed a 300 grm. Guinea-pig within f'orty eight hours, so that the organism is at least of fair average virulence.
By this time the patient had motored back again and for the greater part of the time had been getting about. She was free from organisms in throat or nose (two separate cultures) by May 27.
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