TGF- Signaling

- Methods and Protocols

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indgår i serie METHODS IN MOLECULAR BIOLOGY


TGF-  Signaling
  • Leveringstid 2-4 uger
  • Forventet levering 06-05-2020
Format:
Bog, hardback
Udgivelsesdato:
05-11-2015
Sprog:
Engelsk
Udgave:
1st ed. 2016.
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This volume details up-to-date information and attempts to take the reader into the exciting realm of TGF- from the basic principles to the practical applications. Chapters provide basic introduction of TGF- signaling from the cell surface to the nucleus, methods and techniques for the investigation of TGF- signaling mechanism including receptors, Smads, intracellular kinases, microRNA, epigenetic regulation, post-translational regulations, non-Smad pathway; the physiological implications including those in cell cycle arrest, epithelial-mesenchymal transition, endothelial cells, adipogenesis, Th differentiation, stem cell, bone remodeling, ovary, zebrofish development, and frog animal capping; and the methodologies including metastasis imaging, 3D morphogenesis, membrane receptor quantification, conditional knockout, bone remodeling, kinase and phosphatase assays, BiFC interaction assays, and genome-wide siRNA screen. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, TGF-Beta Signaling: Methods and Protocols aims to ensure successful results in the further study of this vital field.

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Udgivelsesdato:
05-11-2015
ISBN13:
9781493929658
Vægt:
9992 g
Dybde:
25 mm
Bredde:
178 mm
Højde:
254 mm
Nummer i serien:
1344
Nummer i serien:
1344
Format:
Hardback
Forfattere
Bibliotekernes beskrivelse Chapters provide basic introduction of TGF- signaling from the cell surface to the nucleus, methods and techniques for the investigation of TGF- signaling mechanism including receptors, Smads, intracellular kinases, microRNA, epigenetic regulation, post-translational regulations, non-Smad pathway; 1 Hardback 11 Tables, black and white; XII, 394 p.

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