Resistance to Aromatase Inhibitors in Breast Cancer

indgår i serie Resistance to Targeted Anti Cancer Therapeutics


Studiebog
Resistance to Aromatase Inhibitors in Breast Cancer
Du sparer Spar kr. 55,00 med Shopping-fordele
  • Leveringstid 5-8 hverdage
  • Forventet levering 21-04-2021
For at købe bogen til fordelspris skal du have et medlemskab med Shopping-fordele. Du kan prøve medlemskabet gratis de første 30 dage. Medlemskabet fornyes automatisk og kan altid opsiges. Læs mere om medlemskaber og Shopping-fordele her.
Format:
Bog, paperback
Udgivelsesdato:
01-10-2016
Sprog:
Engelsk
Udgave:
Softcover reprint of the original 1st ed. 2015.
  • Beskrivelse
  • Yderligere info
  • Anmeldelser

Aromatase Inhibitors (AIs) treat postmenopausal estrogen receptor positive tumours, which constitute the majority of breast cancer patients. This comprehensive volume brings together the current knowledge from different relevant areas, including molecular mechanisms and translational aspects of drug resistance in AIs. Topics covered include research, experimental , and clinical data specifically focused on AI resistance in breast cancer. The volume will include three sections. The first section covers general knowledge about aromatase inhibitors, including regulation of aromatase genes, and structure and function of aromatase protein. The second section provides the detailed mechanisms of resistance to AIs, while the third section explores prediction of resistance and potential strategies to overcome resistance. Breast cancer is the most common female cancer and AIs significantly improve treatments outcomes compatibly to previously used endocrine treatments. However 10-15% of post-operative patients develop a relapse during adjuvant treatment with AIs; about 25-50% of the patients do not respond to AIs in neo-adjuvant or metastatic setting, and the majority of metastatic patients who initially respond develop resistance within 3 years. There is an important need to understand these mechanisms of resistance in order to develop methods of preventing or overcoming the resistance to AIs, which will ensure a more successful outcome in treating breast cancer.

Vis mereVis mindre

Udgivelsesdato:
01-10-2016
ISBN13:
9783319382845
Vægt:
4628 g
Dybde:
16 mm
Bredde:
155 mm
Højde:
235 mm
Nummer i serien:
8
Format:
Paperback
Forfattere

    Vis mereVis mindre

    Vis mereVis mindre

    Fandt du ikke hvad du søgte?

    Hvis denne bog ikke er noget for dig, kan du benytte kategorierne nedenfor til at finde andre titler. Klik på en kategori for at se lignende bøger.

    Velkommen til Saxo – din danske boghandel!

    Hos os kan du handle som gæst, Saxo-bruger eller Premium-medlem – du bestemmer helt selv. Skulle du få brug for hjælp, sidder vores kundeservice-team klar ved både telefonerne og tasterne.

    Om fordelspriser hos Saxo

    For at købe bøger til fordelspris, skal du være medlem af Premium, Premium Shopping eller Premium Studie. De første 30 dage er gratis for nye medlemmer. Medlemskabet fornyes automatisk og kan altid opsiges. Læs mere om fordelene ved vores forskellige medlemskaber her.

    Machine Name: SAXO080