Excerpt from Reports of the Trypanosomiasis Expedition to the Congo, 1903-1904: Of the Liverpool School of Tropical Medicine and Medical Parasitology
At the same time the Committee resolved to continue the researches on trypanosomiasis in Liverpool, which had been started by ... Drs. Dutton and todd in Senegambia; Dr. Thomas was appointed to conduct the work, and aided by Dr. Linton experiments were immediately commenced, a preliminary note of their work being embodied in this report. The two groups of observers have throughout worked together, and in order that comparable data might be obtained, selected cases of Sleeping Sickness were, by permission of the Congo Free State authorities, sent to the observers in Liverpool. A later report will be published on these cases. As far as the very numerous and detailed observations of these workers go, they shew that the parasite identified with Sleeping Sickness in Uganda and the Congo does not differ from that described by dutton in the Gambia. This view is also held by laveran and mesnil in France, and bruce in this country. The question of a curative agent has for a considerable time engaged the attention of the members of the research, and experiments are now in progress to find a remedial agent which would have the same effect in trypanosomiasis that quinine has in malaria. A variety of drugs have been used with more or less success; Up-to-date, arsenic and trypan red, an aniline dye introduced by ehrlich and shiga, appear to be the most useful the parasite disappears for a time from the blood, and the life of the animal is prolonged, but with neither of the drugs is an absolute cure attained. A combination of the two appears to Offer better results; a large number of animals infected with different trypanosomes are under treatment. The present report also embodies an important note on the Tsetse-¿ies, by Mr. E. E. Austen, to whom the School is much indebted for describing and identifying the Diptera obtained during the Expedition.
Much important work remains to be done; a further study of the disease from a clinical aspect, extended experiments on the transmission of trypanosomic diseases by biting ¿ies, and researches on the lines of schaudinn's work, together with therapeutical Observations in patients and large animals naturally infected with trypanosomes, are urgently needed.
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