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Bog, paperback Lipids in Protein Misfolding af Olga Gursky

Lipids in Protein Misfolding (ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY, nr. 855)

(Bog, paperback)

26 black & white illustrations, 57 colour illustrations, biography

26 black & white illustrations, 57 colour illustrations, biography

Produktdetaljer:

Sprog:
Engelsk
ISBN-13:
9783319372051
Sideantal:
273
Udgivet:
04-11-2016
Udgave:
Softcover reprint of the original 1st ed. 2015
Nr. i serien:
855
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Forlagets beskrivelse
26 black & white illustrations, 57 colour illustrations, biography
Bibliotekernes beskrivelse
Protein conversion from a water-soluble native conformation to the insoluble aggregates and fibrils, which can deposit in amyloid plaques, underlies more than 20 human diseases, representing a major public health problem and a scientific challenge. Such a conversion is called protein misfolding. Protein misfolding can also involve errors in the topology of the folded proteins and their assembly in lipid membranes. Lipids are found in nearly all amyloid deposits in vivo, and can critically influence protein misfolding in vitro and in vivo in many different ways. This book focuses on recent advances in our understanding of the role of lipids in modulating the misfolding of various proteins. The main emphasis is on the basic biophysical studies that address molecular basis of protein misfolding and amyloid formation, and the role of lipids in this complex process.

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