This volume contains the proceedings of the 12th International Conference on Hybrid Systems Computation and Control (HSCC 2009) held in San Francisco, CaliforniaduringApril13-15,2009. Theannualconferenceonhybridsystems- cuses on researchin embedded, reactive systems involving the interplay between discrete switching and continuous dynamics. HSCC is a forum for academic and industrial researchers and practitioners to exchange information on the latest advancements, both practical and theoretical, in the design, analysis, control, optimization, and implementation of hybrid systems. HSCC 2009 was the 12th in a series of successful meetings. Previous versions wereheld in Berkeley(1998),Nijmegen (1999),Pittsburgh(2000),Rome (2001), PaloAlto (2002), Prague(2003), Philadelphia (2004), Zurich (2005), Santa B- bara (2006), Pisa (2007), and St. Louis (2008). HSCC 2009 was part of the 2nd Cyber-Physical Systems Week (CPSWeek), whichconsistedoftheco-locationofHSCCwiththeInternationalConferenceon Information Processing in Sensor Networks (IPSN) and the Real-Time and - bedded Technology and Applications Symposium (RTAS). Through CPSWeek, the three conferences had joint invited speakers, poster sessions, and joint - cial events. In addition to the workshops sponsored by CPSWeek, HSCC 2009 sponsored two workshops: - NSV II: Second International Workshop on Numerical Software Veri?cation - HSCB 2009: Hybrid Systems Approaches to Computational Biology We would like to thank the authors of submitted papers, the Program C- mittee members, the additional reviewers, the workshop organizers, and the HSCC Steering Committee members for their help in composing a strong p- gram. We also thank the CPSWeek Organizing Committee, in particular Rajesh Gupta, for their strenuous work in handling the local arrangements.
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