Streaming af e- og lydbøger Stream e- og lydbøger Prøv gratis

Formulation of Phenytoin Complexes for Dissolution Enhancement

af

Du sparer 11% fra forlagets pris Du sparer 20% fra forlagets pris
Formulation of Phenytoin Complexes for Dissolution Enhancement
  • Forlagets pris kr. 659,95
  • Leveringstid 5-9 hverdage
  • Forventet levering 27-07-2018
Køb til medlemspris og få altid fri fragt.
Prøv 14 dage gratis (herefter 79,-/md.).

Læs mere om Saxo Premium her.
  • Op til 70% rabat
  • Fri fragt
  • Stream 30.000 e- og lydbøger
Bog, hæftet (kr. 529,95) (kr. 589,95)
  1. Beskrivelse

    Phenytoin Inclusion complex prepared by microwave method was used for preparation of FDT by different superdisintegrants by direct compression method. From that the cross-povidone (5%) containing inclusion complex was maximum DT, Wetting time and In-vitro drug release. The FDT containing 1:2 ratio complexes and 5% crospovidone give minimum DT and Wetting time. Then 32 full factorial designs were applied and the tablets were synthesized using different proportions of inclusion complex and crospovidone (%) by direct compression technique. The optimum ratio was 1:2 and 5% which produced highest DT (10.01 sec), Wetting time (9.45 sec.) and cumulative percent drug release (99.51% at 40 min). The solubility and dissolution pattern of Phenytoin were found to be carrier ratio dependent. From evaluation parameters and formulation characterization, it can be concluded that solubility of drug was improved by MW method compared to SE method and pure drug. The tablet contain optimum ratio of inclusion complex and optimum concentration of superdisintegrants give maximum drug release in minimum time period.

  2. Yderligere info
    Udgivelsesdato:
    01-05-2014
    Sprog:
    Engelsk
    ISBN13:
    9783659537059
    Sidetal:
    152
    Vægt:
    236 g
    Højde:
    9 mm
    Bredde:
    152 mm
    Længde:
    229 mm
    Mærkat:
    Bog, hæftet
    Format:
    Hæftet
  3. Anmeldelser

    Kundernes boganmeldelser af Formulation of Phenytoin Complexes for Dissolution Enhancement

Fandt du ikke hvad du søgte?

Hvis denne bog ikke er noget for dig, kan du benytte kategorierne nedenfor til at finde andre titler. Klik på en kategori for at se lignende bøger.