Co-signal Molecules in T Cell Activation

- Immune Regulation in Health and Disease

af

indgår i serie ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY


Studiebog
Co-signal Molecules in T Cell Activation
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Format:
Bog, paperback
Udgivelsesdato:
31-12-2020
Sprog:
Engelsk
Udgave:
1st ed. 2019.
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This book equips young immunologists and health professionals with a clear understanding of the fundamental concepts and roles of co-signal molecules and in addition presents the latest information on co-stimulation. The first part of the book is devoted to co-signal molecules and the regulation of T cells. Following an initial overview, subsequent chapters examine each co-signal molecule in turn and discuss the mechanisms by which co-signal molecules regulate the different types of T cell. The second part covers various clinical applications, including in autoimmune disease, neurological disorders, transplantation, graft-versus-host disease, and cancer immunotherapy. To date, co-stimulation blockade and co-inhibition blockade have shown beneficial effects and many additional clinical trials targeting co-signal molecules are ongoing. The mechanisms underlying these successful treatments are explained and the future therapeutic potential in the aforementioned diseases is evaluated. Co-signal Molecules in T Cell Activation will be a valuable reference guide to co-stimulation for basic and clinical researchers in the fields of both immunology and pharmaceutical science.

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Udgivelsesdato:
31-12-2020
ISBN13:
9789813297197
Vægt:
603 g
Bredde:
155 mm
Højde:
235 mm
Nummer i serien:
1189
Format:
Paperback
Forfattere
Bibliotekernes beskrivelse This book equips young immunologists and health professionals with a clear understanding of the fundamental concepts and roles of co-signal molecules and in addition presents the latest information on co-stimulation. 1 Paperback / softback 50 Tables, color; 21 Illustrations, color; 1 Illustrations, black and white; VI, 326 p. 22 illus., 21 illus. in color.

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