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Bog, paperback Asymmetric Synthesis of Bioactive Lactones and the Development of a Catalytic Asymmetric Synthesis of Alpha-Aryl Ketones af Robert Doran

Asymmetric Synthesis of Bioactive Lactones and the Development of a Catalytic Asymmetric Synthesis of Alpha-Aryl Ketones (Springer Theses)

(Bog, paperback)

255 black & white illustrations, 3 colour illustrations, biography

255 black & white illustrations, 3 colour illustrations, biography

Produktdetaljer:

Sprog:
Engelsk
ISBN-13:
9783319370347
Sideantal:
223
Udgivet:
04-11-2016
Udgave:
Softcover reprint of the original 1st ed. 2015
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(Bog, hardback), Engelsk
kr. 742,78
 
kr. 1.069,95
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2-4 uger
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11-01-2017
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Forlagets beskrivelse
255 black & white illustrations, 3 colour illustrations, biography
Bibliotekernes beskrivelse
This thesis addresses two fundamental areas in contemporary organic chemistry: synthesis of natural products and catalytic asymmetric synthesis. Firstly, a new methodology, developed by our research group, which allows the asymmetric synthesis of lactones, a structural unit ubiquitous in natural products, was utilised in the synthesis of a number of natural product analogues that showed significant biological activity. Secondly, the development of a catalytic asymmetric synthesis of a key structural motif present in a number of natural products and pharmaceuticals was accomplished. During the course of this work we discovered dual stereo control, which is significant because it allows the configuration of a new stereo centre to be controlled by a simple change of proton source.

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