Apoptosis in Health and Disease

- Clinical and Therapeutic Aspects

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Apoptosis in Health and Disease
  • Leveringstid 2-3 uger
  • Forventet levering 10-12-2019
Format:
Bog, paperback
Udgivelsesdato:
26-01-2012
Sprog:
Engelsk
  • Beskrivelse
  • Yderligere info
  • Anmeldelser

The process of programmed cell death or apoptosis has, in the decade preceding the publication of this 2005 book, been shown to be centrally involved in the pathogenesis of the significant majority of human illnesses and injury states. The cellular attrition observed in most degenerative conditions is apoptotic in nature; conversely a failure of apoptosis has been proposed to underlie many forms of cancer. The central role of apoptosis in human disease clearly brings with it clinical promise; for example, the strong possibility exists that attenuation of apoptotic death will significantly modulate the severity of degenerative disorders. Similarly, conditions, such as cancer, autoimmune disease, psoriasis and endometriosis, in which aberrant cellular proliferation is observed, may benefit from enhanced rates of apoptosis. This book surveys the underlying molecular mechanisms of apoptosis, investigates its role in degenerative and other diseases, and evaluates potential therapies that will permit appropriate activation or inhibition of apoptosis in disease and injury states.

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Udgivelsesdato:
26-01-2012
ISBN13:
9780521159449
Vægt:
430 g
Dybde:
14 mm
Bredde:
170 mm
Højde:
244 mm
Format:
Paperback
  • Forfattere

  • Bibliotekernes beskrivelse

    Programmed cell death or apoptosis is centrally involved in the pathogenesis of many significant human illnesses and injury states, including cancer, autoimmune disease, psoriasis, and other degenerative conditions. This 2005 book surveys the underlying molecular mechanisms of apoptosis, investigates its role in degenerative and other diseases, and evaluates potential therapies. Worked examples or Exercises

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