An Introduction to Statistics in Early Phase Trials

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An Introduction to Statistics in Early Phase Trials
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Format:
Bog, hardback
Udgivelsesdato:
16-03-2010
Sprog:
Engelsk
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All new medicines and devices undergo early phase trials to assess,interpret and better understand their efficacy, tolerability andsafety. An Introduction to Statistics in Early Phase Trialsdescribes the practical design and analysis of these importantearly phase clinical trials and provides the crucial statisticalbasis for their interpretation. It clearly and concisely providesan overview of the most common types of trials undertaken in earlyphase clinical research and explains the different methodologiesused. The impact of statistical technologies on clinicaldevelopment and the statistical and methodological basis for makingclinical and investment decisions are also explained.* Conveys key ideas in a concise manner understandable bynon-statisticians * Explains how to optimise designs in a constrained or fixedresource setting * Discusses decision making criteria at the end of Phase IItrials * Highlights practical day-to-day issues and reporting of earlyphase trials An Introduction to Statistics in Early Phase Trials is anessential guide for all researchers working in early phase clinicaltrial development, from clinical pharmacologists andpharmacokineticists through to clinical investigators and medicalstatisticians. It is also a valuable reference for teachers andstudents of pharmaceutical medicine learning about the design andanalysis of clinical trials.

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Udgivelsesdato:
16-03-2010
ISBN13:
9780470059852
Vægt:
628 g
Dybde:
21 mm
Bredde:
175 mm
Højde:
251 mm
Format:
Hardback
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    This guide offers an overview of the most common types of trial undertaken in early clinical development. The coverage discusses the different methodologies and the impact of new technologies, both clinical and statistical, on clinical development.

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